CHICAGO — Chicago’s favorite party aunt is coming to Netflix next week with a show that will star the Twitter account’s raunchy and frank humor — and Chicago itself.

Chris Witaske, who stepped out of the shadows as the formerly anonymous @chipartyaunt account’s creator this summer, said his animated “Chicago Party Aunt” Netflix series is meant to be a love letter to Chicago.

Block Club Chicago spoke with the show’s lead actors and creators, many of whom are from or have lived in the city, about what viewers can expect once the show drops on Netflix Sept. 17. 

The show centers around Diane Dunbrowski, a middle-aged woman who lives in Wrigleyville and is a proud Chicagoan and diehard Cubs fan. Viewers will watch her navigate an increasingly wacky life and see how she solves the challenges thrown at her with her eccentric ways. 

Dunbrowski’s nephew, Daniel, moves in after deciding to take a gap year before going to Stanford. Though their personalities and approaches to life are different, the heart of the show revolves around their relationship and the ways they support each other. 

Actress Lauren Ash, who voices the lead character, previously lived in Chicago and did comedy at Second City. 

“If you aren’t familiar with Chicago, I think the themes that we present and the jokes are universal, and I think that people are going to really have the relationship between Diane and Daniel resonate with them,” Ash said. “I keep saying that people are going to come for the joke, but they’re going to stay for the heart.”

Cleveland actor Rory O’Malley, who voices Daniel and played King George III in Broadway’s “Hamilton,” said Diane and Daniel’s relationship is reflective of his own upbringing. 

“I love the Midwest lifestyle, which is a lot about family, and I was raised by a whole pack of aunts,” said O’Malley, who is from Ohio. “I had a few ‘Chicago Party Aunts’ — Cleveland Party Aunts — and I love the relationship between these two characters, between Diane and Daniel.

“They’re hilarious because they’re opposites, but it’s also beautiful and heartwarming. And I think a lot of people in the Midwest are going to identify with it.”

Watch the accompanying interviews with the cast below.